Frontiers in Pediatrics (Apr 2022)

Multisystemic Inflammatory Syndrome in Children From the South of Colombia: One Year of Experience

  • Pilar Pérez López,
  • Pilar Pérez López,
  • Pilar Pérez López,
  • Darling Carvajal Duque,
  • Darling Carvajal Duque,
  • Doris Martha Salgado García,
  • Martha Rocío Vega Vega,
  • Martha Rocío Vega Vega,
  • Jorge Andrés Ramos-Castaneda,
  • Iván José Ardila Gómez,
  • Iván José Ardila Gómez,
  • Iván José Ardila Gómez,
  • Andrés Felipe Romero,
  • Andrés Felipe Romero,
  • Andrés Felipe Romero

DOI
https://doi.org/10.3389/fped.2022.838922
Journal volume & issue
Vol. 10

Abstract

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BackgroundMultisystemic inflammatory syndrome in children (MIS-C) is one of the most severe presentations of COVID-19 infection in pediatrics. Currently, we have few studies that describe the characteristics of this condition in Colombian children.ObjectiveTo describe the clinical and epidemiological characteristics of children hospitalized with MIS-C in Neiva, Colombia.MethodsObservational follow-up study of a cohort of children with MIS-C for 12 months (May 15, 2020, to May 30, 2021) in two hospitals in the city of Neiva. Epidemiological data, clinical characteristics, laboratory characteristics, cardiological evaluation, treatment, and clinical outcomes were analyzed.ResultsWe included 34 patients who met the diagnosis of MIS-C. The median age was 68 months. Some type of nutritional issue was observed by 43.75% of those under 5 years of age and by 27.78% of those over 5 years of age. Gastrointestinal symptoms were the most frequent, with vomiting, diarrhea, and abdominal pain being the most frequent by 79, 70, and 67%, respectively. By 77% of the patients, a history of SARS-COV-2 infection was documented through IgG. In the echocardiogram, 35.4% of the patients had systolic dysfunction, followed by coronary involvement by 35%.ConclusionThis study describes a series of cases of children with MIS-C in Colombia. Gastrointestinal manifestations were predominant. Mortality was high in comparison to other countries but similar to that reported in Colombia. This fact was associated with relevant pathological background. More training is required for physicians in order to have a better understanding of the disease so as to have an early diagnosis and timely treatment.

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