Antimicrobial Sensitivity in Enterobacteria from AIDS Patients, Zambia

Abstract

Enterobacteria contribute to two serious clinical syndromes seen in African AIDS patients: diarrhea and septicemia. In West Africa, prophylaxis with sulfamethoxazole-trimethoprim (SXT) reduced illnesses. We report reduced sensitivity of enterobacteria to available antimicrobial agents in Zambia, with only 22% of nontyphoidal salmonellae and 6% of shigellae sensitive to SXT.

Keywords

• antimicrobial resistance
• enterobacteria
• septicemia
• diarrhea
• Africa
• HIV infection