Nature Communications (Nov 2020)

Horizontally acquired papGII-containing pathogenicity islands underlie the emergence of invasive uropathogenic Escherichia coli lineages

  • Michael Biggel,
  • Basil B. Xavier,
  • James R. Johnson,
  • Karen L. Nielsen,
  • Niels Frimodt-Møller,
  • Veerle Matheeussen,
  • Herman Goossens,
  • Pieter Moons,
  • Sandra Van Puyvelde

DOI
https://doi.org/10.1038/s41467-020-19714-9
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 15

Abstract

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Escherichia coli is a major cause of urinary tract infection. Here, Biggel et al. provide a phylogenomic analysis of 907 clinical E. coli isolates and identify the P-fimbriae-encoding locus associated with invasive uropathogenic E. coli isolates.