Nature Communications (May 2022)
Genomic analyses of 10,376 individuals in the Westlake BioBank for Chinese (WBBC) pilot project
- Pei-Kuan Cong,
- Wei-Yang Bai,
- Jin-Chen Li,
- Meng-Yuan Yang,
- Saber Khederzadeh,
- Si-Rui Gai,
- Nan Li,
- Yu-Heng Liu,
- Shi-Hui Yu,
- Wei-Wei Zhao,
- Jun-Quan Liu,
- Yi Sun,
- Xiao-Wei Zhu,
- Pian-Pian Zhao,
- Jiang-Wei Xia,
- Peng-Lin Guan,
- Yu Qian,
- Jian-Guo Tao,
- Lin Xu,
- Geng Tian,
- Ping-Yu Wang,
- Shu-Yang Xie,
- Mo-Chang Qiu,
- Ke-Qi Liu,
- Bei-Sha Tang,
- Hou-Feng Zheng
Affiliations
- Pei-Kuan Cong
- Diseases & Population (DaP) Geninfo Lab, School of Life Sciences, Westlake University
- Wei-Yang Bai
- Diseases & Population (DaP) Geninfo Lab, School of Life Sciences, Westlake University
- Jin-Chen Li
- Department of Neurology, Xiangya Hospital, Central South University
- Meng-Yuan Yang
- Diseases & Population (DaP) Geninfo Lab, School of Life Sciences, Westlake University
- Saber Khederzadeh
- Diseases & Population (DaP) Geninfo Lab, School of Life Sciences, Westlake University
- Si-Rui Gai
- Diseases & Population (DaP) Geninfo Lab, School of Life Sciences, Westlake University
- Nan Li
- The High-Performance Computing Center, Westlake University
- Yu-Heng Liu
- The High-Performance Computing Center, Westlake University
- Shi-Hui Yu
- Clinical Genome Center, KingMed Diagnostics, Co., Ltd.
- Wei-Wei Zhao
- Clinical Genome Center, KingMed Diagnostics, Co., Ltd.
- Jun-Quan Liu
- Clinical Genome Center, KingMed Diagnostics, Co., Ltd.
- Yi Sun
- Clinical Genome Center, KingMed Diagnostics, Co., Ltd.
- Xiao-Wei Zhu
- Diseases & Population (DaP) Geninfo Lab, School of Life Sciences, Westlake University
- Pian-Pian Zhao
- Diseases & Population (DaP) Geninfo Lab, School of Life Sciences, Westlake University
- Jiang-Wei Xia
- Diseases & Population (DaP) Geninfo Lab, School of Life Sciences, Westlake University
- Peng-Lin Guan
- Diseases & Population (DaP) Geninfo Lab, School of Life Sciences, Westlake University
- Yu Qian
- Diseases & Population (DaP) Geninfo Lab, School of Life Sciences, Westlake University
- Jian-Guo Tao
- Diseases & Population (DaP) Geninfo Lab, School of Life Sciences, Westlake University
- Lin Xu
- WBBC Shandong Center, Binzhou Medical University
- Geng Tian
- WBBC Shandong Center, Binzhou Medical University
- Ping-Yu Wang
- WBBC Shandong Center, Binzhou Medical University
- Shu-Yang Xie
- WBBC Shandong Center, Binzhou Medical University
- Mo-Chang Qiu
- WBBC Jiangxi Center, Jiangxi Medical College
- Ke-Qi Liu
- WBBC Jiangxi Center, Jiangxi Medical College
- Bei-Sha Tang
- Department of Neurology, Xiangya Hospital, Central South University
- Hou-Feng Zheng
- Diseases & Population (DaP) Geninfo Lab, School of Life Sciences, Westlake University
- DOI
- https://doi.org/10.1038/s41467-022-30526-x
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 15
Abstract
Biobanks of genetic data have been primarily in European populations, which gives us an incomplete understanding of complex traits across populations. Here, the authors initiate the Westlake BioBank for Chinese (WBBC) pilot project with 4,535 whole genome sequences and 5,841 high-density genotypes from China, characterizing large-scale genomic variation in Chinese populations.