Proteome Dynamics during Antibiotic Persistence and Resuscitation
Maja Semanjski,
Fabio Lino Gratani,
Till Englert,
Payal Nashier,
Viktor Beke,
Nicolas Nalpas,
Elsa Germain,
Shilpa George,
Christiane Wolz,
Kenn Gerdes,
Boris Macek
Affiliations
Maja Semanjski
Quantitative Proteomics, Interfaculty Institute of Cell Biology, Faculty of Science, University of Tuebingen, Tuebingen, Germany
Fabio Lino Gratani
Quantitative Proteomics, Interfaculty Institute of Cell Biology, Faculty of Science, University of Tuebingen, Tuebingen, Germany
Till Englert
Quantitative Proteomics, Interfaculty Institute of Cell Biology, Faculty of Science, University of Tuebingen, Tuebingen, Germany
Payal Nashier
Quantitative Proteomics, Interfaculty Institute of Cell Biology, Faculty of Science, University of Tuebingen, Tuebingen, Germany
Viktor Beke
Quantitative Proteomics, Interfaculty Institute of Cell Biology, Faculty of Science, University of Tuebingen, Tuebingen, Germany
Nicolas Nalpas
Quantitative Proteomics, Interfaculty Institute of Cell Biology, Faculty of Science, University of Tuebingen, Tuebingen, Germany
Elsa Germain
Centre for Bacterial Stress Response and Persistence, Section for Functional Genomics, Department of Biology, University of Copenhagen, Copenhagen, Denmark
Shilpa George
Medical Microbiology and Hygiene, Faculty of Science, University of Tuebingen, Tuebingen, Germany
Christiane Wolz
Medical Microbiology and Hygiene, Faculty of Science, University of Tuebingen, Tuebingen, Germany
Kenn Gerdes
Centre for Bacterial Stress Response and Persistence, Section for Functional Genomics, Department of Biology, University of Copenhagen, Copenhagen, Denmark
Boris Macek
Quantitative Proteomics, Interfaculty Institute of Cell Biology, Faculty of Science, University of Tuebingen, Tuebingen, Germany
While bactericidal antibiotics typically require actively growing cells to exploit their function, persister cells are slowly replicating which makes them tolerant to the lethal action of antimicrobials. Here, we used an established in vitrohipAhipB
