Elevated Prostate Health Index (phi) and Biopsy Reclassification During Active Surveillance of Prostate Cancer

Darian Andreas; Jeffrey J. Tosoian; Patricia Landis; Sacha Wolf; Stephanie Glavaris; Tamara L. Lotan; Edward M. Schaeffer; Lori J. Sokoll; Ashley E. Ross

doi:10.1016/j.eucr.2016.04.012

Urology Case Reports (Jul 2016)

Elevated Prostate Health Index (phi) and Biopsy Reclassification During Active Surveillance of Prostate Cancer

Darian Andreas,
Jeffrey J. Tosoian,
Patricia Landis,
Sacha Wolf,
Stephanie Glavaris,
Tamara L. Lotan,
Edward M. Schaeffer,
Lori J. Sokoll,
Ashley E. Ross

Affiliations

Darian Andreas: The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Jeffrey J. Tosoian: The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Patricia Landis: The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Sacha Wolf: The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Stephanie Glavaris: The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Tamara L. Lotan: Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Edward M. Schaeffer: Department of Urology, Northwestern University, Chicago, IL 60611, USA
Lori J. Sokoll: The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Ashley E. Ross: The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA

DOI: https://doi.org/10.1016/j.eucr.2016.04.012
Journal volume & issue: Vol. 7, no. C
pp. 64 – 66

Abstract

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The Prostate Health Index (phi) has been FDA approved for decision-making regarding prostate biopsy. Phi has additionally been shown to positively correlate with tumor volume, extraprostatic disease and higher Gleason grade tumors. Here we describe a case in which an elevated phi encouraged biopsy of a gentleman undergoing active surveillance leading to reclassification of his disease as high risk prostate cancer.

Published in Urology Case Reports

ISSN: 2214-4420 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the genitourinary system. Urology
Website: http://www.urologycasereports.com/

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Abstract

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