Российский кардиологический журнал (May 2020)

The non-compacted myocardium in patients with hemochromatosis: a phenomenon or cardiopathy? The role of magnetic resonance imaging and molecular genetics in diagnosis

  • E. A. Mershina,
  • O. V. Kulikova,
  • R. P. Myasnikov,
  • E. A. Lukina,
  • A. N. Meshkov,
  • A. V. Kiseleva,
  • P. S. Pilyus,
  • S. N. Koretsky,
  • M. S. Kharlap,
  • R. V. Ponomarev,
  • N. V. Tsvetaeva,
  • O. F. Nikulina,
  • S. A. Boytsov,
  • V. E. Sinitsyn,
  • O. M. Drapkina

DOI
https://doi.org/10.15829/1560-4071-2020-3759
Journal volume & issue
Vol. 25, no. 4

Abstract

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This article presents the results of studies on high prevalence of left ventricular noncompaction (LVNC) in patients with secondary hemochromatosis (SH). We also included case reports of patients with SH and LVNC and compared imaging data using modified modern criteria for LVNC and molecular genetic testing (MGT). In patients with cardiac hemochromatosis, left ventricular noncompaction is noted, the nature of which is most likely secondary. In order to confirm this hypothesis, a prospective observational study, including family screening and MGT, is required.

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