Marine Drugs (Oct 2020)

The Chemistry, Biochemistry and Pharmacology of Marine Natural Products from <i>Leptolyngbya,</i> a Chemically Endowed Genus of Cyanobacteria

  • Yueying Li,
  • C. Benjamin Naman,
  • Kelsey L. Alexander,
  • Huashi Guan,
  • William H. Gerwick

DOI
https://doi.org/10.3390/md18100508
Journal volume & issue
Vol. 18, no. 10
p. 508

Abstract

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Leptolyngbya, a well-known genus of cyanobacteria, is found in various ecological habitats including marine, fresh water, swamps, and rice fields. Species of this genus are associated with many ecological phenomena such as nitrogen fixation, primary productivity through photosynthesis and algal blooms. As a result, there have been a number of investigations of the ecology, natural product chemistry, and biological characteristics of members of this genus. In general, the secondary metabolites of cyanobacteria are considered to be rich sources for drug discovery and development. In this review, the secondary metabolites reported in marine Leptolyngbya with their associated biological activities or interesting biosynthetic pathways are reviewed, and new insights and perspectives on their metabolic capacities are gained.

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