Serum cytokine and chemokine profiles of patients with confirmed bacterial and viral meningitis

Abstract

Introduction: Cerebrospinal fluid (CSF) cytokines and chemokines have been reported by several studies as useful markers to discriminate bacterial and viral meningitis (BM and VM). This study aimed to investigate if serum cytokine and chemokine profiles could also differentiate BM from VM, thus circumventing the need for an invasive lumbar puncture.

Keywords

• machine learning
• random forest
• meningitis diagnosis
• differential cytokine pattern
• serum cytokines chemokines