Nature Communications (Nov 2019)

Genomic data integration by WON-PARAFAC identifies interpretable factors for predicting drug-sensitivity in vivo

  • Yongsoo Kim,
  • Tycho Bismeijer,
  • Wilbert Zwart,
  • Lodewyk F. A. Wessels,
  • Daniel J. Vis

DOI
https://doi.org/10.1038/s41467-019-13027-2
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 12

Abstract

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Integrative analyses that link molecular data to treatment sensitivity are essential for precision medicine. Here the authors introduce WON-PARAFAC to integrate multiple genomics data to identify sparse and interpretable factors.