A critical appraisal of the clinical utility of proton therapy in oncology

Medical Devices : Evidence and Research. 2015;2015(default):439-446


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Journal Title: Medical Devices : Evidence and Research

ISSN: 1179-1470 (Online)

Publisher: Dove Medical Press

LCC Subject Category: Medicine: Medicine (General): Medical technology

Country of publisher: United Kingdom

Language of fulltext: English

Full-text formats available: PDF, HTML



Wang D


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Time From Submission to Publication: 16 weeks


Abstract | Full Text

Dongxu WangDepartment of Radiation Oncology, University of Iowa Hospitals and Clinics, Iowa City, IA, USAAbstract: Proton therapy is an emerging technology for providing radiation therapy to cancer patients. The depth dose distribution of a proton beam makes it a preferable radiation modality as it reduces radiation to the healthy tissue outside the tumor, compared with conventional photon therapy. While theoretically beneficial, its clinical values are still being demonstrated from the increasing number of patients treated with proton therapy, from several dozen proton therapy centers around the world. High equipment and facility costs are often the major obstacle for its wider adoption. Because of the high cost and lack of definite clinical evidence of its superiority, proton therapy treatment faces criticism on its cost-effectiveness. Technological development is causing a gradual lowering of costs, and research and clinical studies are providing further evidence on its clinical utility.Keywords: proton therapy, radiation, cancer, oncology