Nature Communications (Apr 2022)

Temporal and spatial characterisation of protein liquid-liquid phase separation using NMR spectroscopy

  • Jack E. Bramham,
  • Alexander P. Golovanov

DOI
https://doi.org/10.1038/s41467-022-29408-z
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 11

Abstract

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Protein liquid-liquid phase separation is an important phenomenon in biology. Here, the authors demonstrate an approach to characterize the evolution of protein phases in both time and space using a fluorinated probe molecule in NMR spectroscopy.