Case Reports in Dentistry (Jan 2021)

Unusual Variant of Unicystic Ameloblastoma with CEOT-Like Areas: A Rare Case Report with Review of Literature

  • Venkata Ramanand Oruganti,
  • Shylaja Sanjeevareddygari,
  • Manay Srinivas Munisekhar,
  • Sharath Kumar Reddy Eppalapalli,
  • Raghu Vamshi Vishwakarma,
  • Kiran Kumar Ganji,
  • Kiran R. Halkai,
  • Rahul Halkai

DOI
https://doi.org/10.1155/2021/2093927
Journal volume & issue
Vol. 2021

Abstract

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Ameloblastoma is an epithelial odontogenic neoplasm with clinical and histological diversity. They are locally invasive tumors with 3 clinical variants such as solid, unicystic, and peripheral ameloblastomas, and the unicystic variant constitutes only 13%. Histologically, it shows diverse microscopic patterns that may occur isolated or in combination with other patterns. The granular cell variant accounts for 3.5% of all ameloblastoma cases. The eosinophilic granules seen in the cytoplasm of the tumor are thought to be lysosomes and presumably contribute to the pathogenesis of the tumor. Although such a phenomenon is rare in unicystic ameloblastoma, granular cell differentiation in solid multicystic ameloblastoma is a well-established phenomenon. In this paper, we present a unique case of unicystic ameloblastoma with granular cell differentiation with a brief review.