Infection and Drug Resistance (Jan 2024)
A Case Report of Urinary Tract Infection and Fungemia Due to Pichia ohmeri Complicated with Pulmonary Thromboembolism
Abstract
Jiang-Jie Sun,1,2 Rui Shi,1,2 He Huang1,2 1Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong Province, 518035, People’s Republic of China; 2Department of Pulmonary and Critical Care Medicine, Shenzhen Second People’s Hospital, Shenzhen, Guangdong Province, 518035, People’s Republic of ChinaCorrespondence: He Huang, Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Shenzhen University, No. 3002 Sungang Road, Futian District, Shenzhen, Guangdong Province, 518035, People’s Republic of China, Email [email protected]: Pichia ohmeri (P. ohmeri) is a rare human pathogen known to cause severe conditions such as sepsis, fungemia, endocarditis, and peritonitis, often resulting in high mortality rates. This report presents a case of a febrile 66-year-old male with a urinary tract infection and fungemia caused by P. ohmeri. The patient had additional complications of pulmonary thromboembolism (PTE) and deep venous thrombosis (DVT) in the left lower extremity. Notably, the pathogen was isolated in both urine and blood cultures, an uncommon finding in immunocompetent patients. Treatment with fluconazole was initiated based on the antifungal susceptibility testing (AFST) results. Following treatment, the patient experienced a gradual resolution of fever and urinary tract infection symptoms. Concurrently, anticoagulant therapy was administered for the management of PTE and DVT. The patient was eventually discharged in a stable condition.Keywords: Pichia ohmeri, fungemia, urinary tract infection, pulmonary thromboembolism, deep venous thrombosis
