Frontiers in Neurology (Sep 2019)
Simulation-Based Training of the Rapid Evaluation and Management of Acute Stroke (STREAM)—A Prospective Single-Arm Multicenter Trial
- Ferdinand O. Bohmann,
- Natalia Kurka,
- Richard du Mesnil de Rochemont,
- Katharina Gruber,
- Joachim Guenther,
- Peter Rostek,
- Heike Rai,
- Philipp Zickler,
- Michael Ertl,
- Ansgar Berlis,
- Sven Poli,
- Sven Poli,
- Annerose Mengel,
- Annerose Mengel,
- Peter Ringleb,
- Simon Nagel,
- Johannes Pfaff,
- Frank A. Wollenweber,
- Lars Kellert,
- Moriz Herzberg,
- Luzie Koehler,
- Karl Georg Haeusler,
- Karl Georg Haeusler,
- Anna Alegiani,
- Charlotte Schubert,
- Caspar Brekenfeld,
- Christopher E. J. Doppler,
- Oezguer A. Onur,
- Christoph Kabbasch,
- Tanja Manser,
- Waltraud Pfeilschifter,
- STREAM Trial Investigators,
- Mohammad Alotaibi,
- AbdulAziz Batarfi,
- Annemarie Brandhofe,
- Roxane-Isabelle Kestner,
- Jan Hendrik Schaefer,
- Martin Alexander Schaller,
- Alexander Seiler,
- Stephanie Wallenwein,
- Laurent M. Willems,
- Helmuth Steinmetz,
- Elke Hattingen,
- Zeljko Kos,
- Markus Naumann,
- Corinna Blum,
- Paula Bombach,
- Julia Zeller,
- Christoph Gumbinger,
- Jens Regula,
- Solveig Horstmann,
- Miriam Heyse,
- Eva Dorozewski,
- Christian Hamentner,
- Reiff Tilman,
- Simon Schieber,
- Sibu Mundiyanapurath,
- Silvia Schönenberger,
- Yahia Mokli,
- Markus Möhlenbruch,
- Jan Bewersdorf,
- Maximilian Einhäupl,
- Katharina Feil,
- Matthias Klein,
- Ken Möhwald,
- Konstanze Mühlbauer,
- Mathias Mulazzani,
- Guido Rohrer,
- Sonja Schönecker,
- Franziska Dorn,
- Philipp Mennemeyer,
- Torleif Sandner,
- Brigitte Huber,
- Julia Hill,
- Jela Gavran,
- Heinrich Audebert,
- Rohat Geran,
- Johannes Schurig,
- Juliane Herm,
- Felix Kleefeld,
- Karl Schoknecht,
- Denes Jadranka,
- Kirsten Brade,
- Tatjana Wittenberg,
- Ulrich Mayer-Runge,
- Maxim Bester,
- Michael H Schönfeld,
- Fabian Flottmann,
- Lisa Prilop,
- Hannes Leischner,
- Andreas Maximilian Frölich,
- Sabine Roesner,
- Gabriel Broocks,
- Uta Hanning,
- Stephanie Guder,
- Matthias Bechstein,
- Caspar Brekenfeld,
- Carmen Lange,
- Sebastian Kautz,
- Focko L. Higgen,
- Anna Kyselyova,
- Götz Thomalla,
- Jens Fiehler,
- Gereon Rudolf Fink,
- Anna Bonkhoff,
- Julian Dronse,
- Katharina Kirsch,
- Sarah Laurent,
- Boris von Reutern,
- Jurij Rosen,
- Lukas Volz,
- Jan-Michael Werner,
- Michael Wollring,
- Robert Seliger,
- Abdulkadir Yildirim,
- Marc Schlamann,
- Jan Borggrefe
Affiliations
- Ferdinand O. Bohmann
- Department of Neurology, University Hospital Frankfurt, Frankfurt, Germany
- Natalia Kurka
- Department of Neurology, University Hospital Frankfurt, Frankfurt, Germany
- Richard du Mesnil de Rochemont
- Institute for Diagnostic and Interventional Neuroradiology, University Hospital Frankfurt, Frankfurt, Germany
- Katharina Gruber
- Department of Neurology, University Hospital Frankfurt, Frankfurt, Germany
- Joachim Guenther
- Department of Neurology, Klinikum Hanau, Hanau, Germany
- Peter Rostek
- NICU Nursing Staff, University Hospital Frankfurt, Frankfurt, Germany
- Heike Rai
- Department of Neurology, University Hospital Frankfurt, Frankfurt, Germany
- Philipp Zickler
- Department of Neurology and Clinical Neurophysiology, Universitätsklinikum Augsburg, Augsburg, Germany
- Michael Ertl
- Department of Neurology and Clinical Neurophysiology, Universitätsklinikum Augsburg, Augsburg, Germany
- Ansgar Berlis
- Department for Diagnostic and Interventional Radiology and Neuroradiology, Universitätsklinikum Augsburg, Augsburg, Germany
- Sven Poli
- Department of Neurology With Focus on Neurovascular Diseases and Neurooncology, University Hospital Tübingen, Tübingen, Germany
- Sven Poli
- Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany
- Annerose Mengel
- Department of Neurology With Focus on Neurovascular Diseases and Neurooncology, University Hospital Tübingen, Tübingen, Germany
- Annerose Mengel
- Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany
- Peter Ringleb
- Department of Neurology, University Hospital Heidelberg, Heidelberg, Germany
- Simon Nagel
- Department of Neurology, University Hospital Heidelberg, Heidelberg, Germany
- Johannes Pfaff
- 0Department of Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany
- Frank A. Wollenweber
- 1Department of Neurology, Ludwig Maximilians-University, Munich, Germany
- Lars Kellert
- 1Department of Neurology, Ludwig Maximilians-University, Munich, Germany
- Moriz Herzberg
- 2Department for Diagnostic and Interventional Neuroradiology, Ludwig Maximilians-University, Munich, Germany
- Luzie Koehler
- 3Department of Neurology, University Hospital Leipzig, Leipzig, Germany
- Karl Georg Haeusler
- 4Centre for Stroke Research Berlin, Charité—Universitätsmedizin Berlin, Berlin, Germany
- Karl Georg Haeusler
- 5Department of Neurology, Universitätsklinikum Würzburg, Würzburg, Germany
- Anna Alegiani
- 6Department of Neurology, University Medical Centre Hamburg Eppendorf, Hamburg, Germany
- Charlotte Schubert
- 6Department of Neurology, University Medical Centre Hamburg Eppendorf, Hamburg, Germany
- Caspar Brekenfeld
- 7Department of Diagnostic and Interventional Neuroradiology, University Medical Centre Hamburg Eppendorf, Hamburg, Germany
- Christopher E. J. Doppler
- 8Department of Neurology, University Hospital Cologne, Cologne, Germany
- Oezguer A. Onur
- 8Department of Neurology, University Hospital Cologne, Cologne, Germany
- Christoph Kabbasch
- 9Department of Neuroradiology, University Hospital Cologne, Cologne, Germany
- Tanja Manser
- 0School of Applied Psychology, FHNW University of Applied Sciences and Arts Northwestern Switzerland, Olten, Switzerland
- Waltraud Pfeilschifter
- Department of Neurology, University Hospital Frankfurt, Frankfurt, Germany
- STREAM Trial Investigators
- Mohammad Alotaibi
- AbdulAziz Batarfi
- Annemarie Brandhofe
- Roxane-Isabelle Kestner
- Jan Hendrik Schaefer
- Martin Alexander Schaller
- Alexander Seiler
- Stephanie Wallenwein
- Laurent M. Willems
- Helmuth Steinmetz
- Elke Hattingen
- Zeljko Kos
- Markus Naumann
- Corinna Blum
- Paula Bombach
- Julia Zeller
- Christoph Gumbinger
- Jens Regula
- Solveig Horstmann
- Miriam Heyse
- Eva Dorozewski
- Christian Hamentner
- Reiff Tilman
- Simon Schieber
- Sibu Mundiyanapurath
- Silvia Schönenberger
- Yahia Mokli
- Markus Möhlenbruch
- Jan Bewersdorf
- Maximilian Einhäupl
- Katharina Feil
- Matthias Klein
- Ken Möhwald
- Konstanze Mühlbauer
- Mathias Mulazzani
- Guido Rohrer
- Sonja Schönecker
- Franziska Dorn
- Philipp Mennemeyer
- Torleif Sandner
- Brigitte Huber
- Julia Hill
- Jela Gavran
- Heinrich Audebert
- Rohat Geran
- Johannes Schurig
- Juliane Herm
- Felix Kleefeld
- Karl Schoknecht
- Denes Jadranka
- Kirsten Brade
- Tatjana Wittenberg
- Ulrich Mayer-Runge
- Maxim Bester
- Michael H Schönfeld
- Fabian Flottmann
- Lisa Prilop
- Hannes Leischner
- Andreas Maximilian Frölich
- Sabine Roesner
- Gabriel Broocks
- Uta Hanning
- Stephanie Guder
- Matthias Bechstein
- Caspar Brekenfeld
- Carmen Lange
- Sebastian Kautz
- Focko L. Higgen
- Anna Kyselyova
- Götz Thomalla
- Jens Fiehler
- Gereon Rudolf Fink
- Anna Bonkhoff
- Julian Dronse
- Katharina Kirsch
- Sarah Laurent
- Boris von Reutern
- Jurij Rosen
- Lukas Volz
- Jan-Michael Werner
- Michael Wollring
- Robert Seliger
- Abdulkadir Yildirim
- Marc Schlamann
- Jan Borggrefe
- DOI
- https://doi.org/10.3389/fneur.2019.00969
- Journal volume & issue
-
Vol. 10
Abstract
Introduction: Acute stroke care delivered by interdisciplinary teams is time-sensitive. Simulation-based team training is a promising tool to improve team performance in medical operations. It has the potential to improve process times, team communication, patient safety, and staff satisfaction. We aim to assess whether a multi-level approach consisting of a stringent workflow revision based on peer-to-peer review and 2–3 one-day in situ simulation trainings can improve acute stroke care processing times in high volume neurocenters within a 6 months period.Methods and Analysis: The trial is being carried out in a pre-test-post-test design at 7 tertiary care university hospital neurocenters in Germany. The intervention is directed at the interdisciplinary multiprofessional stroke teams. Before and after the intervention, process times of all direct-to-center stroke patients receiving IV thrombolysis (IVT) and/or endovascular therapy (EVT) will be recorded. The primary outcome measure will be the “door-to-needle” time of all consecutive stroke patients directly admitted to the neurocenters who receive IVT. Secondary outcome measures will be intervention-related process times of the fraction of patients undergoing EVT and effects on team communication, perceived patient safety, and staff satisfaction via a staff questionnaire.Interventions: We are applying a multi-level intervention in cooperation with three “STREAM multipliers” from each center. First step is a central meeting of the multipliers at the sponsor's institution with the purposes of algorithm review in a peer-to-peer process that is recorded in a protocol and an introduction to the principles of simulation training and debriefing as well as crew resource management and team communication. Thereafter, the multipliers cooperate with the stroke team trainers from the sponsor's institution to plan and execute 2–3 one-day simulation courses in situ in the emergency department and CT room of the trial centers whereupon they receive teaching materials to perpetuate the trainings.Clinical Trial Registration: STREAM is a registered trial at https://clinicaltrials.gov/ct2/show/NCT03228251.
Keywords