mBio
(Apr 2021)
Saccharomyces cerevisiae Requires
<i>CFF1</i>
To Produce 4-Hydroxy-5-Methylfuran-3(2H)-One, a Mimic of the Bacterial Quorum-Sensing Autoinducer AI-2
Julie S. Valastyan,
Christina M. Kraml,
Istvan Pelczer,
Thomas Ferrante,
Bonnie L. Bassler
Affiliations
Julie S. Valastyan
Department of Molecular Biology, Princeton University, Princeton, New Jersey, USA
Christina M. Kraml
Lotus Separations LLC, Department of Chemistry, Princeton University, Princeton, New Jersey, USA
Istvan Pelczer
Department of Chemistry, Princeton University, Princeton, New Jersey, USA
Thomas Ferrante
Department of Molecular Biology, Princeton University, Princeton, New Jersey, USA
Bonnie L. Bassler
ORCiD Department of Molecular Biology, Princeton University, Princeton, New Jersey, USA
DOI
https://doi.org/10.1128/mBio.03303-20
Journal volume & issue
Vol. 12,
no. 2
Abstract
Read online
Quorum sensing is a cell-to-cell communication process that bacteria use to monitor local population density. Quorum sensing relies on extracellular signal molecules called autoinducers (AIs).
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