Nature Communications (Feb 2022)

Characterising within-hospitalSARS-CoV-2 transmission events using epidemiological and viral genomic data across two pandemic waves

  • Benjamin B. Lindsey,
  • Ch. Julián Villabona-Arenas,
  • Finlay Campbell,
  • Alexander J. Keeley,
  • Matthew D. Parker,
  • Dhruv R. Shah,
  • Helena Parsons,
  • Peijun Zhang,
  • Nishchay Kakkar,
  • Marta Gallis,
  • Benjamin H. Foulkes,
  • Paige Wolverson,
  • Stavroula F. Louka,
  • Stella Christou,
  • Amy State,
  • Katie Johnson,
  • Mohammad Raza,
  • Sharon Hsu,
  • Thibaut Jombart,
  • Anne Cori,
  • Sheffield COVID-19 Genomics Group,
  • The COVID-19 Genomics UK (COG-UK) consortium,
  • CMMID COVID-19 working group,
  • Cariad M. Evans,
  • David G. Partridge,
  • Katherine E. Atkins,
  • Stéphane Hué,
  • Thushan I. de Silva

DOI
https://doi.org/10.1038/s41467-022-28291-y
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 11

Abstract

Read online

SARS-CoV-2 has resulted in multiple outbreaks in hospitals, but identifying transmission events is challenging. Here, the authors combine whole genome sequencing and epidemiological data from the first two waves of the pandemic at a UK hospital trust and characterise transmission chains.