Gender-based differences of inflammatory, coagulation, and cardiac markers in COVID-19 patients in Erbil city

Abstract

In December 2019, a new coronavirus disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appeared in Wuhan city and quickly became a global health issue. COVID-19 causes various symptoms ranging from no symptoms to potentially deadly pneumonia. The study aimed to understand the effects of SARS-CoV-2 infection on immune response and the differences in inflammatory, coagulation, and cardiac biomarkers between male and female patients. Between June 1st and November 1st, 2020, 95 cases of SARS-CoV-2 infected individuals were studied at Zanko Hospital. SARSCoV-2 infection was confirmed using the real-time RT-PCR technique. All cases were analyzed for clinical, epidemiological, and laboratory data. On average, the patients were 50.64 (SEM= 2.359) years old, with 61 males and 34 females. Thepatients had elevated C-reactive protein (CRP), which was 43.96 (SEM= 6.154), while the erythrocyte sedimentation rate (ESR) was 50.50 (SEM= 5.498). The mean of D-Dimer, ferritin and lactate dehydrogenase (LDH) were 1.204 (SEM= 0.164), 534.7 (SEM= 61.48),and 366.6 (SEM= 36.81), respectively. There were no significant differences in the study's data mentioned above between male and female patients. In conclusion, inflammation is the most prominent symptom in COVID-19 patients, and males and females are nearly equally affected

Keywords

• covid-19,
• d-dimer,
• inflammatory markers,
• ldh,
• sex difference