The Tumor Necrosis Factor Alpha and Interleukin 6 Auto-paracrine Signaling Loop Controls Mycobacterium avium Infection via Induction of IRF1/IRG1 in Human Primary Macrophages

mBio (Oct 2021)

Affiliations

Alexandre Gidon: Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, Trondheim, Norway
Claire Louet: Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, Trondheim, Norway
Lisa Marie Røst: Department of Biotechnology and Food Science, Faculty of Natural Sciences, Norwegian University of Science and Technology, Trondheim, Norway
Per Bruheim: Department of Biotechnology and Food Science, Faculty of Natural Sciences, Norwegian University of Science and Technology, Trondheim, Norway
Trude Helen Flo: ORCiD; Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, Trondheim, Norway

Abstract

The prevalence of lung diseases caused by nontuberculous mycobacteria, such as Mycobacterium avium