Evaluation of the Systemic Immune Inflammatory Response in Cases Infected with Helicobacter Pylori

Abstract

INTRODUCTION: The effectiveness of systemic immune inflammation index (SII), which is a practical, new, and useful marker in indicating inflammation, in various malignant and non-malignant diseases has been shown. In the present study, it was aimed to examine the correlation between Helicobacter pylori (HP)+, which causes chronic infection and inflammation, and SII. METHODS: A total of 88 HP+ cases and 154 HP− control cases were included our retrospective, randomized, and controlled study. HP+- was assessed according to the endoscopic biopsy reports of cases. All secondary causes that may lead to inflammation were excluded from the study. The SI level of the case and control groups was calculated (absolute neutrophil × absolute platelet/absolute lymphocyte). RESULTS: In our study, no significant correlation between HP+, a chronic infection, and SII could not be shown (p>0.05). It was detected that HP+ was more common in young ages (p<0.05). DISCUSSION AND CONCLUSION: The results of our study suggest that SII may not be a useful marker in indicating HP+ as we could not find a significant correlation between SII and HP+.

Keywords

• endoscopy
• helicobacter pylori
• systemic immune inflamatory index.