mBio (Oct 2021)

Global Transcriptional Repression of Diguanylate Cyclases by MucR1 Is Essential for <i>Sinorhizobium</i> -Soybean Symbiosis

  • Meng-Lin Li,
  • Jian Jiao,
  • Biliang Zhang,
  • Wen-Tao Shi,
  • Wen-Hao Yu,
  • Chang-Fu Tian

DOI
https://doi.org/10.1128/mBio.01192-21
Journal volume & issue
Vol. 12, no. 5

Abstract

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The ubiquitous second messenger c-di-GMP is well-known for its role in biofilm formation and host adaptation of pathogens, whereas it is less investigated in mutualistic symbioses. Here, we reveal a cocktail of eight functional diguanylate cyclases (DGCs) catalyzing the biosynthesis of c-di-GMP in a broad-host-range Sinorhizobium