Nature Communications (Nov 2019)

Programmed DNA elimination of germline development genes in songbirds

  • Cormac M. Kinsella,
  • Francisco J. Ruiz-Ruano,
  • Anne-Marie Dion-Côté,
  • Alexander J. Charles,
  • Toni I. Gossmann,
  • Josefa Cabrero,
  • Dennis Kappei,
  • Nicola Hemmings,
  • Mirre J. P. Simons,
  • Juan Pedro M. Camacho,
  • Wolfgang Forstmeier,
  • Alexander Suh

DOI
https://doi.org/10.1038/s41467-019-13427-4
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 10

Abstract

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Songbirds have extensive germline–soma genome differences due to developmental elimination of a germline-specific chromosome (GRC). Here, the authors show that the GRC contains dozens of expressed developmental genes, some of which have been on the GRC since the ancestor of all songbirds.