Drug Repurposing Campaigns for Human Cytomegalovirus Identify a Natural Compound Targeting the Immediate-Early 2 (IE2) Protein: A Comment on “The Natural Flavonoid Compound Deguelin Inhibits HCMV Lytic Replication within Fibroblasts”
Beatrice Mercorelli,
Anna Luganini,
Giorgio Palù,
Giorgio Gribaudo,
Arianna Loregian
Affiliations
Beatrice Mercorelli
Department of Molecular Medicine, University of Padua, 35121 Padua, Italy
Anna Luganini
Department of Life Sciences and Systems Biology, University of Turin, 10123 Turin, Italy
Giorgio Palù
Department of Molecular Medicine, University of Padua, 35121 Padua, Italy
Giorgio Gribaudo
Department of Life Sciences and Systems Biology, University of Turin, 10123 Turin, Italy
Arianna Loregian
Department of Molecular Medicine, University of Padua, 35121 Padua, Italy
Human cytomegalovirus (HCMV) is a ubiquitous herpesvirus that establishes a lifelong persistence in the host through both chronic and latent states of infection [...]