Drug Repurposing Campaigns for Human Cytomegalovirus Identify a Natural Compound Targeting the Immediate-Early 2 (IE2) Protein: A Comment on “The Natural Flavonoid Compound Deguelin Inhibits HCMV Lytic Replication within Fibroblasts”

Beatrice Mercorelli; Anna Luganini; Giorgio Palù; Giorgio Gribaudo; Arianna Loregian

doi:10.3390/v11020117

Viruses (Jan 2019)

Drug Repurposing Campaigns for Human Cytomegalovirus Identify a Natural Compound Targeting the Immediate-Early 2 (IE2) Protein: A Comment on “The Natural Flavonoid Compound Deguelin Inhibits HCMV Lytic Replication within Fibroblasts”

Beatrice Mercorelli,
Anna Luganini,
Giorgio Palù,
Giorgio Gribaudo,
Arianna Loregian

Affiliations

Beatrice Mercorelli: Department of Molecular Medicine, University of Padua, 35121 Padua, Italy
Anna Luganini: Department of Life Sciences and Systems Biology, University of Turin, 10123 Turin, Italy
Giorgio Palù: Department of Molecular Medicine, University of Padua, 35121 Padua, Italy
Giorgio Gribaudo: Department of Life Sciences and Systems Biology, University of Turin, 10123 Turin, Italy
Arianna Loregian: Department of Molecular Medicine, University of Padua, 35121 Padua, Italy

DOI: https://doi.org/10.3390/v11020117
Journal volume & issue: Vol. 11, no. 2
p. 117

Abstract

Read online

Human cytomegalovirus (HCMV) is a ubiquitous herpesvirus that establishes a lifelong persistence in the host through both chronic and latent states of infection [...]

n/a

Published in Viruses

ISSN: 1999-4915 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Microbiology
Website: http://www.mdpi.com/journal/viruses

About the journal

Abstract

Keywords