mBio
(Apr 2021)
Extent of Cytomegalovirus Replication in the Human Host Depends on Variations of the HLA-E/UL40 Axis
Hannes Vietzen,
Timo Rückert,
Svenja Hartenberger,
Claudia Honsig,
Peter Jaksch,
Silvana Geleff,
Quirin Hammer,
Chiara Romagnani,
Maia Segura-Wang,
Elisabeth Puchhammer-Stöckl
Affiliations
Hannes Vietzen
Center for Virology, Medical University of Vienna, Vienna, Austria
Timo Rückert
Innate Immunity, German Rheumatism Research Center, Leibniz Association, Berlin, Germany
Svenja Hartenberger
Center for Virology, Medical University of Vienna, Vienna, Austria
Claudia Honsig
Division of Clinical Virology, Medical University of Vienna, Vienna, Austria
Peter Jaksch
Division of Thoracic Surgery, Medical University of Vienna, Vienna, Austria
Silvana Geleff
Clinical Institute of Pathology, Medical University of Vienna, Vienna, Austria
Quirin Hammer
Innate Immunity, German Rheumatism Research Center, Leibniz Association, Berlin, Germany
Chiara Romagnani
Innate Immunity, German Rheumatism Research Center, Leibniz Association, Berlin, Germany
Maia Segura-Wang
Center for Virology, Medical University of Vienna, Vienna, Austria
Elisabeth Puchhammer-Stöckl
ORCiD Center for Virology, Medical University of Vienna, Vienna, Austria
DOI
https://doi.org/10.1128/mBio.02996-20
Journal volume & issue
Vol. 12,
no. 2
Abstract
Read online
Infection with human cytomegalovirus (HCMV) is associated with substantial morbidity in immunosuppressed patients and after congenital infections. Therefore, development of a vaccine against HCMV is a main public health priority.
WeChat QR code
Close
