International Journal of Molecular Sciences (Jul 2020)

<i>Artemisia annua</i>, a Traditional Plant Brought to Light

  • Axelle Septembre-Malaterre,
  • Mahary Lalarizo Rakoto,
  • Claude Marodon,
  • Yosra Bedoui,
  • Jessica Nakab,
  • Elisabeth Simon,
  • Ludovic Hoarau,
  • Stephane Savriama,
  • Dominique Strasberg,
  • Pascale Guiraud,
  • Jimmy Selambarom,
  • Philippe Gasque

DOI
https://doi.org/10.3390/ijms21144986
Journal volume & issue
Vol. 21, no. 14
p. 4986

Abstract

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Traditional remedies have been used for thousand years for the prevention and treatment of infectious diseases, particularly in developing countries. Of growing interest, the plant Artemisia annua, known for its malarial properties, has been studied for its numerous biological activities including metabolic, anti-tumor, anti-microbial and immunomodulatory properties. Artemisia annua is very rich in secondary metabolites such as monoterpenes, sesquiterpenes and phenolic compounds, of which the biological properties have been extensively studied. The purpose of this review is to gather and describe the data concerning the main chemical components produced by Artemisia annua and to describe the state of the art about the biological activities reported for this plant and its compounds beyond malaria.

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