Managing Wound Healing with a High-Risk Patient: A Case Report
Nikolai N. Potekaev,
Olga B. Borzykh,
German V. Medvedev,
Marina M. Petrova,
Elena I. Karpova,
Maria A. Zatolokina,
Mustafa Al-Zamil,
Olga M. Demina,
Ekaterina A. Narodova,
Natalia A. Shnayder
Affiliations
Nikolai N. Potekaev
Department of Skin Disease and Cosmetology, Pirogov Russian National Research Medical University, 117997 Moscow, Russia
Olga B. Borzykh
Department of Shared Core Facilities “Molecular and Cell Technologies”, Voino-Yasenetsky Krasnoyarsk State Medical University, 660022 Krasnoyarsk, Russia
German V. Medvedev
Department of Hand Surgery with Microsurgical Equipment, R. R. Vreden National Medical Research Centre for Traumatology and Orthopedics, 195427 Saint Petersburg, Russia
Marina M. Petrova
Department of Shared Core Facilities “Molecular and Cell Technologies”, Voino-Yasenetsky Krasnoyarsk State Medical University, 660022 Krasnoyarsk, Russia
Elena I. Karpova
Department of Skin Disease and Cosmetology, Pirogov Russian National Research Medical University, 117997 Moscow, Russia
Maria A. Zatolokina
Department of Histology, Embryology, Cytology, Medical Faculty, Kursk State Medical University, 305014 Kursk, Russia
Mustafa Al-Zamil
Department of Physiotherapy, Faculty of Continuing Medical Education, Peoples’ Friendship University of Russia, 117198 Moscow, Russia
Olga M. Demina
Department of Skin Disease and Cosmetology, Pirogov Russian National Research Medical University, 117997 Moscow, Russia
Ekaterina A. Narodova
Department of Shared Core Facilities “Molecular and Cell Technologies”, Voino-Yasenetsky Krasnoyarsk State Medical University, 660022 Krasnoyarsk, Russia
Natalia A. Shnayder
Department of Shared Core Facilities “Molecular and Cell Technologies”, Voino-Yasenetsky Krasnoyarsk State Medical University, 660022 Krasnoyarsk, Russia
Wound healing is a complex, multi-step process. This process begins immediately after skin damage. The outcome of wound healing depends on the quality of each stage of this process: a normal or pathological scar. Violation of wound healing entails a decrease in the function of scar tissue as well as aesthetic dissatisfaction with the patient. This problem is especially important in aesthetic surgery. Patients who have come for beauty feel frustration, obtaining pathological scars. We have been dealing with the problem of wound healing after plastic surgery for about 10 years. Our approach includes the assessment of the risk of pathological wound healing and the treatment of high-risk patients. The risk assessment includes historical data on wound healing, signs of connective tissue dysfunction (especially patients with connective tissue dysplasia), and genetic polymorphisms of genes responsible for the structure of the components of the extracellular matrix of the skin. In the future, patients with a high risk of pathological scarring can be prescribed treatment after surgery. This article presents a clinical case in which we demonstrate our approach.
