Bone Mineral Density and Vitamin D Values in Behçet’s Disease

Abstract

Objective:It was aim to compare the bone mineral density (BMD) and 25-hydroxy vitamin D (25-OH vitamin D) values of the patients with Behçet’s disease (BD) according to healthy population.Materials and Methods:A total of 34 patients diagnosed with BD which was 15 males and 19 females (mean age: 35.1±8.6 years; age range: 19 to 50 years), and 29 controls which was 12 males and 17 females (mean age: 36.9±9.2 years; age range: 21 to 51 years) were included in the study. The lumbar spine (L1-L4 total) measurements were made for the axial skeleton BMD values, and femur total and femur neck measurements were used for the appendicular skeleton BMD values.Results:The patients’ lumbar BMD values were significantly (p0.05). There was no significant correlation between the 25-OH vitamin D values and the BMD values of the groups (p>0.05).Conclusion:Even though the BD has a subclinical inflammatory course, it can cause a reduction of BMD by affecting the bone metabolism. Thus, the patients’ BMD values should be followed up, and when required vitamin D supplements should be administered to prevent the development of secondary osteoporosis.

Keywords

• Behçet’s disease
• bone mineral density
• 25-hydroxy vitamin D