Nature Communications (Jun 2016)

A CD36 ectodomain mediates insect pheromone detection via a putative tunnelling mechanism

  • Carolina Gomez-Diaz,
  • Benoîte Bargeton,
  • Liliane Abuin,
  • Natalia Bukar,
  • Jaime H. Reina,
  • Tudor Bartoi,
  • Marion Graf,
  • Huy Ong,
  • Maximilian H. Ulbrich,
  • Jean-Francois Masson,
  • Richard Benton

DOI
https://doi.org/10.1038/ncomms11866
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 17

Abstract

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The CD36-related Sensory Neuron Membrane Protein 1 (SNMP1) facilitates pheromone detection by insect odorant receptors. Here Gomez-Diaz et al.show that the SNMP1 ectodomain is essential for function and propose that it forms a tunnel that transports pheromones from the extracellular fluid to their cognate receptors.