Frontiers in Pediatrics (Jun 2024)

Synthesis of current pediatric urinary microbiome research

  • Layla M. Jeries,
  • Tatyana A. Sysoeva,
  • Lisa Karstens,
  • Lisa Karstens,
  • Maryellen S. Kelly,
  • Maryellen S. Kelly

DOI
https://doi.org/10.3389/fped.2024.1396408
Journal volume & issue
Vol. 12

Abstract

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The human urinary bladder hosts a complex microbial community of low biomass referred to as the urobiome. While the composition of the urobiome has been investigated in adults for over a decade now, only a few studies have considered the presence and composition of the urobiome in children. It is critical to explore how the urobiome develops throughout the life span and how it changes in the presence of various health conditions. Therefore, we set to review the available data on pediatric urobiome composition and its development with age and disease. In addition, we focused on identifying and reporting specific gaps in our knowledge of the pediatric urobiome that we hope will be addressed by future studies in this swiftly developing field with fast-improving methods and consensus.

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