Annals of Indian Academy of Neurology (Jan 2017)

Optical coherence tomography and subclinical optical neuritis in longitudinally extensive transverse myelitis

  • Prakash Kumar Sinha,
  • Deepika Joshi,
  • Virendra Pratap Singh,
  • Sujit Deshmukh,
  • Usha Singh,
  • Abhishek Pathak,
  • Vijay Nath Mishra,
  • Rameshwar Nath Chaurasia,
  • Vivek Sharda,
  • Garima Gupta

DOI
https://doi.org/10.4103/aian.AIAN_170_17
Journal volume & issue
Vol. 20, no. 4
pp. 358 – 362

Abstract

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Objective: The aim is to compare the retinal nerve fiber layer (RNFL) thickness of longitudinally extensive transverse myelitis (LETM) eyes without previous optic neuritis with that of healthy control subjects. Methods: Over 20 LETM eyes and 20 normal control eyes were included in the study and subjected to optical coherence tomography to evaluate and compare the RNFL thickness. Result: Significant RNFL thinning was observed at 8 o'clock position in LETM eyes as compared to the control eyes (P = 0.038). No significant differences were seen in other RNFL measurements. Conclusion: Even in the absence of previous optic neuritis LETM can lead to subclinical axonal damage leading to focal RNFL thinning.

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