Monasnicotinates A–D, Four New Pyridine Alkaloids from the Fungal Strain Monascus pilosus BCRC 38093

Abstract

Four new pyridine derivatives, monasnicotinates A–D (1–4) were isolated from the red yeast rice of Monascus pilosus BCRC 38093. Their structures were elucidated on the basis of physicochemical evidence, in-depth NMR spectroscopic analysis, and high-resolution mass spectrometry. Their inhibitory effects on NO production was also evaluated.

Keywords

• Monascus pilosus BCRC 38093
• pyridine derivatives
• NO production