Frontiers in Chemistry (Mar 2015)

Exploring the conformational landscape of menthol, menthone, and isomenthone: A microwave study

  • David eSchmitz,
  • V. Alvin Shubert,
  • Thomas eBetz,
  • Melanie eSchnell

DOI
https://doi.org/10.3389/fchem.2015.00015
Journal volume & issue
Vol. 3

Abstract

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The rotational spectra of the monoterpenoids menthol, menthone, and isomenthone are reportedin the frequency range of 2−8.5GHz, obtained with broadband Fourier-transform microwave spectroscopy.For menthol only one conformation was identified under the cold conditions of the molecularjet, whereas three conformations were observed for menthone and one for isomenthone. Theconformational space of the different molecules was extensively studied using quantum chemicalcalculations, and the results were compared with molecular parameters obtained by the measurements.Finally, a computer program is presented, which was developed to automatically identifydifferent species in a dense broadband microwave spectrum using calculated ab initio rotationalconstants as input.

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