Metabolic Syndrome and Menopause: The Impact of Menopause Duration on Risk Factors and Components

Abstract

Kadriye Erdoğan,1 Nevin Sanlier2 1Department of Obstetrics and Gynecology, Health Sciences University, Etlik Zübeyde Hanım Women’s Health Training and Research Hospital, Ankara, Turkey; 2Department of Nutrition and Dietetics, Ankara Medipol University, Ankara, TurkeyCorrespondence: Kadriye Erdoğan, Email [email protected]: This study was undertaken to investigate the impact of menopause duration on the risk factors and components of metabolic syndrome (MetS).Patients and Methods: Women aged between 45 and 60 years participated in the study. Participants were split into two groups based on the duration of menopause. Women who had been menopausal for 1 to ≤ 5 years constituted Group 1, while women with 6– 10 years of menopause duration formed Group 2.Results: Significant differences were observed between the two groups for various factors associated with MetS, including anthropometric measurements, biochemical markers, and blood pressure. The conicity index, weight-to-hip ratio, waist-to-height ratio, visceral adiposity index (VAI), and menopause duration were associated with increased risk of MetS. Our multivariate logistic regression model showed that women with elevated VAI had a 2.073-fold (95% CI: 1.73– 2.48, p< 0.001) increased risk of MetS, while women with menopause duration more than 5 years had a 6.44-fold (95% CI: 3.336– 12.45, p< 0.001) increased risk of MetS.Conclusion: The duration of menopause was found to be linked to a higher risk of MetS. Our results emphasize the importance of monitoring and managing metabolic health in women during the menopausal period, particularly those with extended menopause duration.Keywords: metabolic syndrome, menopause, anthropometric measurements

Keywords

• metabolic syndrome
• menopause
• anthropometric measurements