Scientific Reports (May 2022)

A high resolution scanning electron microscopy analysis of intracranial thrombi embedded along the stent retrievers

  • Daniela Dumitriu LaGrange,
  • Gianmarco Bernava,
  • Philippe Reymond,
  • Isabel Wanke,
  • Maria Isabel Vargas,
  • Paolo Machi,
  • Karl-Olof Lövblad

DOI
https://doi.org/10.1038/s41598-022-11830-4
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 11

Abstract

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Abstract Endovascular treatment with stent retriever thrombectomy is a major advancement in the standard of care in acute ischemic stroke (AIS). The modalities through which thrombi embed along stent retriever following mechanical thrombectomy (MTB) have not yet been elucidated. Using scanning electron microscopy (SEM), we analyzed the appearance of thrombi retrieved by MTB from AIS patients, when embedded into the stent retriever. We observed that the organization and structural compactness vary for compositionally different thrombi. The modalities of attachment onto the stent vary according to thrombus composition and organization.