Photoredox-catalyzed oxo-amination of aryl cyclopropanes

Liang Ge; Ding-Xing Wang; Renyi Xing; Di Ma; Patrick J. Walsh; Chao Feng

doi:10.1038/s41467-019-12403-2

Nature Communications (Sep 2019)

Photoredox-catalyzed oxo-amination of aryl cyclopropanes

Liang Ge,
Ding-Xing Wang,
Renyi Xing,
Di Ma,
Patrick J. Walsh,
Chao Feng

Affiliations

Liang Ge: Institute of Advanced Synthesis (IAS), School of Chemistry and Molecular Engineering, Nanjing Tech University
Ding-Xing Wang: Institute of Advanced Synthesis (IAS), School of Chemistry and Molecular Engineering, Nanjing Tech University
Renyi Xing: Institute of Advanced Synthesis (IAS), School of Chemistry and Molecular Engineering, Nanjing Tech University
Di Ma: Institute of Advanced Synthesis (IAS), School of Chemistry and Molecular Engineering, Nanjing Tech University
Patrick J. Walsh: Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania
Chao Feng: Institute of Advanced Synthesis (IAS), School of Chemistry and Molecular Engineering, Nanjing Tech University

DOI: https://doi.org/10.1038/s41467-019-12403-2
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 9

Abstract

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The ring-opening and functionalization of electronically unbiased cyclopropanes is highly challenging to achieve in a regioselective fashion. Here, the authors report a mild photoredox-coupled oxoamination of electronically unactivated aryl cyclopropanes with simple azaarenes and molecular oxygen.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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