Journal of Cancer Epidemiology (Jan 2024)

Significant Association of PD-L1 With CD44 Expression and Patient Survival: Avenues for Immunotherapy and Cancer Stem Cells Downregulation in Pancreatic Cancers

  • Saleema Mehboob Ali,
  • Yumna Adnan,
  • Zubair Ahmad,
  • Tabish Chawla,
  • S. M. Adnan Ali

DOI
https://doi.org/10.1155/2024/3448648
Journal volume & issue
Vol. 2024

Abstract

Read online

Conclusion: Our findings show a significant association of PD-L1 with CD44 marker expression as well as patient survival. This research shows the potential to serve as the foundation for investigating the efficacy of immunotherapy in reducing CD44-expressing CSCs in pancreatic cancer, potentially enhancing patient outcomes.