Consilium Medicum (Jun 2022)

Retrospective analysis of patients with diabetes mellitus type 2 and acute myocardial infarction

  • Tatiana P. Bardymova,
  • Seseg S. Tsyretorova,
  • Oyuna S. Donirova

DOI
https://doi.org/10.26442/20751753.2022.4.201701
Journal volume & issue
Vol. 24, no. 4
pp. 256 – 260

Abstract

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Background. Acute myocardial infarction (AMI) in patients with type 2 diabetes mellitus (T2DM) is characterized by a severe course and unfavorable clinical outcomes. Accumulating information, which characterize the features of the development of AMI depending on the degree of carbohydrate metabolism disorders (CMD). Aim. To conduct a retrospective analysis of medical records with an assessment of the clinical profiles of the patients with T2DM and AMI. Materials and methods. A retrospective analysis of medical records of patients in the acute period of myocardial infarction over a five-year period was carried out. The exclusion criteria were: unstable or stable angina pectoris. The average values and standard deviations (MSD) were calculated. Comparison of quantitative variables between groups was carried out using the Student's t-test. Absolute (n) and relative (%) values were calculated to describe qualitative data. The value p0.05 was used as the level of statistical significance. Results. The total number of medical records is 7618, of them with AMI 2337 cards, of which 1114 (48%) patients with T2DM, type 1 diabetes mellitus, impaired glucose tolerance/impaired fasting glycemia (IGT/IFG) and AMI, as well as 1223 (52%) patients with AMI without CMD. Among patients with AMI, patients with T2DM and AMI accounted for 23%. Gender differences with female dominance were registered in the group of T2DM and AMI (63%), men dominated among patients with AMI without CMD. In the groups of T2DM and AMI, IGT/IFG and AMI, AMI without CMD, women were older than men (p0.05%). In patients with T2DM and AMI, compared with patients with AMI without CMD, repeated AMI and high mortality are more often registered. The presence of diabetes was associated with a higher incidence of concomitant diseases and the presence of severe complications of the disease. Conclusion. Clinical features of AMI in patients with T2DM are represented by gender-age parameters, characteristics of concomitant pathology and the nature of complications of acute ischemia, the frequency of repeated AMI with an increased risk of adverse outcomes.

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