Perspective for use of the radionuclide drugs in the treatment of malignant tumors in Russiaw

Abstract

This article reviews perspective of the targeted radionuclide therapy (TRT) as one of the rapidly growing fields of nuclear medicine. The characteristics, features of action, advantages and disadvantages of the most used α- and β-emitters (223Ra, 213Bi, 225Ac, 211At, 89Sr, 90Y, 131I, 153Sm, 177Lu) are presented. New approaches based on the use of α-emitting isotopes in the treatment of castration-resistant prostate cancer with bone metastases, acute myeloid leukemia, melanoma, neuroendocrine tumors, and brain tumors are discussed. The importance of TRT in routine clinical practice is underlined. The use of targeted radionuclide therapy in clinical settings in our country should be expanded

Keywords

• радионуклидные лекарственные препараты
• ксофиго
• таргетная радионуклидная терапия
• радиофармпрепараты
• радий-223
• хлорид радия