ALLERGY TO ANTIBIOTICS IN CHILDREN: WHO IS TO BLAME AND WHAT TO DO?

Abstract

Allergic reactions to antibiotics are a serious issue of pediatric practice and a difficult problem for pediatricians due to difficulties of diagnostics, interpretation of anamnestic data and subsequent selection of adequate antibacterial therapy. The review describes the main types of allergic reactions to the antibacterial drugs most widely used in children. Special attention is given to drug hypersensitivity development risk factors; clinical manifestations of allergy to antibiotics and peculiarities of allergic reactions to certain drugs are described. The article dwells upon clinical approaches and algorithms of managing patients with presumed intolerance to antibacterial drugs.

Keywords

• antibiotics
• antibacterial drugs
• allergic reactions
• drug hypersensitivity
• allergy
• intolerance
• risk factors