Reprogramming microbial populations using a programmed lysis system to improve chemical production

Wenwen Diao; Liang Guo; Qiang Ding; Cong Gao; Guipeng Hu; Xiulai Chen; Yang Li; Linpei Zhang; Wei Chen; Jian Chen; Liming Liu

doi:10.1038/s41467-021-27226-3

Nature Communications (Nov 2021)

Reprogramming microbial populations using a programmed lysis system to improve chemical production

Wenwen Diao,
Liang Guo,
Qiang Ding,
Cong Gao,
Guipeng Hu,
Xiulai Chen,
Yang Li,
Linpei Zhang,
Wei Chen,
Jian Chen,
Liming Liu

Affiliations

Wenwen Diao: State Key Laboratory of Food Science and Technology, Jiangnan University
Liang Guo: State Key Laboratory of Food Science and Technology, Jiangnan University
Qiang Ding: State Key Laboratory of Food Science and Technology, Jiangnan University
Cong Gao: State Key Laboratory of Food Science and Technology, Jiangnan University
Guipeng Hu: State Key Laboratory of Food Science and Technology, Jiangnan University
Xiulai Chen: State Key Laboratory of Food Science and Technology, Jiangnan University
Yang Li: State Key Laboratory of Food Science and Technology, Jiangnan University
Linpei Zhang: Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University
Wei Chen: State Key Laboratory of Food Science and Technology, Jiangnan University
Jian Chen: Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University
Liming Liu: State Key Laboratory of Food Science and Technology, Jiangnan University

DOI: https://doi.org/10.1038/s41467-021-27226-3
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 14

Abstract

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Microbial ecosystem-based bioproduction requires the regulation of phenotypic structure of microbial populations. Here, the authors report the construction of a programmed lysis system and its ability for reprograming microbial cooperation in poly(lactate-co-3-hydroxybutyrate) and butyrate production by E. coli strains.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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