Nature Communications (Sep 2021)

Investigating the shared genetic architecture between multiple sclerosis and inflammatory bowel diseases

  • Yuanhao Yang,
  • Hannah Musco,
  • Steve Simpson-Yap,
  • Zhihong Zhu,
  • Ying Wang,
  • Xin Lin,
  • Jiawei Zhang,
  • Bruce Taylor,
  • Jacob Gratten,
  • Yuan Zhou

DOI
https://doi.org/10.1038/s41467-021-25768-0
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 12

Abstract

Read online

An epidemiological association between multiple sclerosis (MS) and inflammatory bowel disease (IBD) is well-established, but a genetic link is unclear. Here, the authors investigate the shared genetic architecture between MS and IBD to shed light on the biological basis of comorbidity.