Nature Communications (Oct 2020)

Increased RNA editing in maternal immune activation model of neurodevelopmental disease

  • Hadas Tsivion-Visbord,
  • Eli Kopel,
  • Ariel Feiglin,
  • Tamar Sofer,
  • Ran Barzilay,
  • Tali Ben-Zur,
  • Orly Yaron,
  • Daniel Offen,
  • Erez Y. Levanon

DOI
https://doi.org/10.1038/s41467-020-19048-6
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 13

Abstract

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Interferon can be induced by the viral mimic PolyI:C, which can in turn activate RNA editing enzymes. Here the authors identify transient changes in A-to-I RNA editing following maternal immune activation in mice.