Squamous Cell Carcinoma Involving Periocular Area

Abstract

Squamous Cell Carcinoma (SCC) involving periocular area accounts for 5-10% of all malignant eyelid neoplasms. Although, periocular SCC is the second most common eyelid malignancy after basal cell carcinoma, but is more aggressive and invasive than basal cell carcinoma. It can metastasize and invade the orbital and intracranial structure, hence it has a considerable potential of mortality and morbidity. We report a case of 35-year-old male with SCC involving periocular area who presented with non-healing ulcer over the skin of upper eyelid, lower eyelid and outer canthus of left eye with Perineural Invasion (PNI) and Lymphovascular Invasion (LVI).

Keywords

• lymphovascular invasion
• perineural invasion
• periocular squamous cell carcinoma