Frontiers in Public Health (Aug 2025)

Peruvian validation and standardization of the TabCAT-brain health assessment

  • Andrés Muñoz-Najar,
  • Andrés Muñoz-Najar,
  • Manuel Montemurro,
  • Manuel Montemurro,
  • María del Carmen Tejada,
  • María del Carmen Tejada,
  • Claudia Rivera-Fernández,
  • Miguel Sánchez-Fernández,
  • Nilton Custodio,
  • Katherine L. Possin,
  • Katherine L. Possin,
  • Elena Tsoy,
  • Elena Tsoy,
  • Serggio Lanata,
  • Serggio Lanata,
  • Marcio Soto-Añari

DOI
https://doi.org/10.3389/fpubh.2025.1600131
Journal volume & issue
Vol. 13

Abstract

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IntroductionDetecting cognitive impairment in low-educated and marginalized populations may result in under- or over-estimation of diagnoses due to reliance on non-validated approaches and normative data. This study validates and standardizes TabCAT-BHA for older adults living in the Andean region of Peru using regression-based normalization.MethodsTwo hundred fifty-eight participants were assessed with the MMSE, RUDAS, and TabCAT-BHA. Classified as either cognitively healthy or impaired based on Clinical Dementia Rating criteria.ResultsBy incorporating sex, place of residence, age, and years of education as covariates, the TabCAT-BHA demonstrated greater accuracy in detecting cognitive impairment (AUC = 75.3%) compared to the MMSE (AUC = 66.4%) and RUDAS (AUC = 71.4%). After incorporating only significant sociodemographic predictors, TabCAT-BHA obtained better AUC (77.4%) compared to MMSE (66.6%) and RUDAS (71.9%).DiscussionThe TabCAT-BHA proves to be a valid tool for detecting cognitive impairment, and incorporating sociodemographic factors improves its accuracy in marginalized settings of Peru.

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