Continuous and Segmented Flow Microfluidics: Applications in High-throughput Chemistry and Biology
Claire E. Stanley,
Robert C. R. Wootton,
Andrew J. deMello
Affiliations
Claire E. Stanley
Institute for Chemical and Bioengineering, Department of Chemistry and Applied Biosciences, ETH Zürich, Wolfgang-Pauli-Strasse 10, CH-8093 Zürich, Switzerland
Robert C. R. Wootton
Institute for Chemical and Bioengineering, Department of Chemistry and Applied Biosciences, ETH Zürich, Wolfgang-Pauli-Strasse 10, CH-8093 Zürich, Switzerland
Andrew J. deMello
Institute for Chemical and Bioengineering, Department of Chemistry and Applied Biosciences, ETH Zürich, Wolfgang-Pauli-Strasse 10, CH-8093 Zürich, Switzerland. [email protected]
This account highlights some of our recent activities focused on developing microfluidic technologies for application in high-throughput and high-information content chemical and biological analysis. Specifically, we discuss the use of continuous and segmented flow microfluidics for artificial membrane formation, the analysis of single cells and organisms, nanomaterial synthesis and DNA amplification via the polymerase chain reaction. In addition, we report on recent developments in small-volume detection technology that allow access to the vast amounts of chemical and biological information afforded by microfluidic systems.
