Catalytic activity of some oxime-based Pd(II)-complexes in Suzuki coupling of aryl and heteroaryl bromides in water

Abstract

The catalytic activity of four Pd(II)-complexes of benzoazole-oximes was extensively studied in Suzuki–Miyaura C–C cross coupling reactions in water, as an eco-friendly green solvent, under both thermal heating as well as microwave irradiation conditions. The cross-coupling reactions included different activated and deactivated aryl- or heteroaryl-bromides with several arylboronic acids. The protected oxime-complexes were found to be more efficient than the free ones.

Keywords

• Palladium
• Catalysis
• Suzuki coupling
• Water solvent
• Aryl bromides
• Arylboronic acids