Optimising the treatment for uncomplicated acute appendicitis (OPTIMA trial): a protocol for a multicentre, randomised, double-blinded placebo-controlled study

• Jie Wu,
• Xiuwen Wu,
• Jianan Ren,
• Robert Sawyer,
• Haiyang Jiang,
• Shikuan Li,
• Peige Wang

Affiliations

Jie Wu

Non-communicable Disease Prevention, Nanjing Municipal Center for Disease Control and Prevention, Nanjing, China

Xiuwen Wu

1 Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China

Jianan Ren

1 Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China

Robert Sawyer

Department of Surgery, Western Michigan University, Kalamazoo, Michigan, USA

Haiyang Jiang

Department of General Surgery, The Affiliated BenQ Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China

Shikuan Li

Department of Emergency Medicine, The Affiliated Hospital of Qingdao University, Qingdao, China

Peige Wang

Department of Emergency Medicine, The Affiliated Hospital of Qingdao University, Qingdao, China