To Chemistry Journal (Aug 2019)
Antioxidant and Antipyretic Activities of Adansonia Digitata (African Baobab) Fruit, Leaf And Bark Extracts
Abstract
The study was conducted to evaluate the antioxidant and antipyretic activity of Adansonia digitata (African Baobab) fruit, leaf and bark extracts. Antioxidant activity of plant part extracts were determined by free radical Diphenylpicrylhydrazyl (DPPH) assay while the antipyretic activity was assessed using experimental animals. Antioxidant activity of leaf extract showed a value of 13.40±0.77, bark extract 29.23±1.69 while fruit extract gave a value of 39.21±2.26. For the Antipyretic activity results, the average temperature of Albino Wister rats was 21.65±0.96 oC before fever inducement and 30.64±1.37 oC after inducement. Following the administration of the leaf extract (400 mg/kg and 800 mg/kg), bark extract (400 mg/kg and 800 mg/kg) and fruit extract (400 mg/kg and 800 mg/kg), the body temperature of the albino rats fell to25.96±1.16 oC vs. 25.28±1.13 oC, 26.06±1.17 oC vs. 25.02±1.12 oC, and 25.78±1.15 oC vs. 24.30±1.09 oC respectively. The results showed that the fruit extract has a higher antioxidant and antipyretic activity than bark and leaf extracts.
