Epigenetic regulation of SARS-Cov-2 spike protein modulates cellular viability and nascent RNA transcription in neuronal cells

• Xi Kong,
• Peng Lu,
• Jinyue Zhang,
• Zheng Bao,
• Chenghao Kuang,
• Bingqing Xie,
• Jianhua Peng,
• Ning Ma,
• Yong Jiang,
• Shigang Yin

Affiliations

Xi Kong

Laboratory of Neurological Diseases and Brain Function, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China; Institute of Epigenetics and Brain Science, Southwest Medical University, Luzhou, Sichuan 646000, China

Peng Lu

Laboratory of Neurological Diseases and Brain Function, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China; Department of Neurosurgery, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China

Jinyue Zhang

Laboratory of Neurological Diseases and Brain Function, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China; Institute of Epigenetics and Brain Science, Southwest Medical University, Luzhou, Sichuan 646000, China

Zheng Bao

Laboratory of Neurological Diseases and Brain Function, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China; Institute of Epigenetics and Brain Science, Southwest Medical University, Luzhou, Sichuan 646000, China

Chenghao Kuang

Laboratory of Neurological Diseases and Brain Function, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China; Institute of Epigenetics and Brain Science, Southwest Medical University, Luzhou, Sichuan 646000, China

Bingqing Xie

Institute of Epigenetics and Brain Science, Southwest Medical University, Luzhou, Sichuan 646000, China

Jianhua Peng

Laboratory of Neurological Diseases and Brain Function, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China; Institute of Epigenetics and Brain Science, Southwest Medical University, Luzhou, Sichuan 646000, China; Department of Neurosurgery, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China

Ning Ma

Inflammation and Allergic Diseases Research Unit, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China; Corresponding author. Laboratory of Neurological Diseases and Brain Function, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China.

Yong Jiang

Laboratory of Neurological Diseases and Brain Function, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China; Institute of Epigenetics and Brain Science, Southwest Medical University, Luzhou, Sichuan 646000, China; Department of Neurosurgery, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China; Corresponding author. Laboratory of Neurological Diseases and Brain Function, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China.

Shigang Yin

Laboratory of Neurological Diseases and Brain Function, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China; Institute of Epigenetics and Brain Science, Southwest Medical University, Luzhou, Sichuan 646000, China; Corresponding author. Laboratory of Neurological Diseases and Brain Function, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China.