Química Nova (Sep 2015)

SÍNTESE DE N-GLICOSILSULFONAMIDAS DERIVADAS DE D-GLICOSE E N-ACETILGLICOSAMINA

  • Lucas L. Franco,
  • Mário C. Brandão,
  • José D. S. Filho,
  • Ricardo J. Alves

DOI
https://doi.org/10.5935/0100-4042.20150110
Journal volume & issue
Vol. 38, no. 8
pp. 1044 – 1052

Abstract

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Herein, we report the synthesis of β-N-glycosylsulfonamides derivatives of D-glucose and N-acetylglucosamine using conventional methods. We also describe a procedure that allows the preparation of these compounds in good yields without the anomerization of the intermediate glycosylamines. This method includes the intermediates obtained from the less reactive 1- and 2-naphthalenesulfonyl chlorides.

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